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Exclusive! Why Pyridine Is Used In Acetylation

The principle is the same. Phenols are not acetylated by acetic anhydride alone in carbon tetrachloride but addition of pyridine leads to acetylation.


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An acid anhydride can also be used as the acylating agent.

Why pyridine is used in acetylation. Pyridine acts as a nucleophilic catalyst and generates the same intermediate as above.


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